Hepatotoxicity studies of sub-chronic administration of aqueous stem bark of khaya senegalensis in albino rats

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Potency of Aqueous Stem Bark Extract of Khaya Senegalensis against Liver Diseases in Rats

In order to assess the potency of aqueous stem bark extract of Khaya senegalensis (KS) against liver diseases, serum aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) were assayed in rats treated with two (2) different doses of the extract after the induction of liver damage in the rats using carbon tetrachloride, CCl4. The rats treated with a daily dose of...

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Effect of Aqueous Stem Bark Extract of Khaya senegalensis on Some Biochemical, Haematological, and Histopathological Parameters of Rats

The subchronic effect of aqueous stem bark extract of Khaya senegalensis on some biochemical, haematological, and histopathological parameters of rats was investigated. The rats were divided into six groups of five rats per group. Groups I to VI were administered graded doses of 0, 400, 800, 1200, 1600, and 2000 mg/kg bw, respectively. The result of study revealed that administration of the Kha...

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For Khaya Senegalensis ( Australian Mahogany ) Bark Extract

The bitter tasting bark is used for a variety of medical purposes. An extract of the bark of Khaya senegalensis is commonly used in African traditional medicine for pain and inflammation, against fever caused by malaria, stomach complaints and headaches. It is widely used in the treatment of fever, malaria, to cure skin rashes, wounds, mucous diarrhea, as an anti-microbial agent in venereal dis...

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Increased liver alkaline phosphatase and aminotransferase activities following administration of ethanolic extract of Khaya senegalensis stem bark to rats

The effect of daily, oral administration of ethanolic extract of Khaya senegalensis stem bark (2mg/kg body weight) for 18days on the alkaline phosphatase, aspartate and alanine aminotransferase activities of rat liver and serum were investigated. Compared with the control, the activities of liver alkaline phosphatase (ALP), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) inc...

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ژورنال

عنوان ژورنال: Bayero Journal of Pure and Applied Sciences

سال: 2010

ISSN: 2006-6996,2006-6996

DOI: 10.4314/bajopas.v3i1.58560